products

Expanded Primary Cells have been developed to give researchers the opportunity to work with cells which closely resemble the in vivo situation. The cells are brought back into proliferation without altering their most relevant tissue-specific characteristics such as transporters or enzyme...

Patch Ready Cells are pre‐qualified aliquots of cryopreserved cells which can be used in patch clamp assays without prior cultivation. The set of cell lines expresses pharmaceutically relevant ion channels including the six cardiac channels of the CiPA panel. The ion channel cell lines have been...

Epithelial cells exert a barrier function in the human body and thereby determines the fate of chemicals and drugs in absorption, distribution, metabolism and excretion (ADME). To investigate the uptake of compounds and tissue specific toxicity is a critical step in the drug development process. To...

instaCELL cytotoxicity assay kits have been designed to improve the reliability and reproducibility of routine toxicity testing. The assay kit includes aliquots of cryopreserved assay ready cells which have been qualified for the testing. The cells can be used like a reagent instantly after thawing...

Allergic contact dermatitis is an environmental health issue induced by chemicals. A set of alternative methods has been approved by the OECD to test potential skin sensitizers in vitro. The cell‐based assays represent early key events of the skin sensitization process. h‐CLAT, the human Cell Line...

Chemicals or other environmental noxes which damage the DNA or interfere with cell division, may impact the genomic integrity of cells. This can result in cell death and cancer. To screen chemicals for their genotoxic and mutagenic potential multiple types of assays have been developed. A cell‐based...