products

Byonoy has developed a new generation of compact and easy to use microplate readers with a foot-print not much larger than the assay plate itself. Within seconds, 96 detection units simultaneously read the signal of individual wells. There are no moving parts involved. The built-in assay protocol is...

Medical devices and material which comes in contact with a patient must be tested for biocompatibility before a product can released for the market. As part of this, the cytotoxicity of extracts prepared from the materials is addressed. Sensitive indicator cells like L-929 mouse fibroblasts are...

instaCELL cytotoxicity assay kits have been designed to improve the reliability and reproducibility in routine toxicity testing. The assay kit includes aliquots of cryopreserved assay ready cells which have been optimized and validated for the particular purpose. The cells can be used like a reagent...

Cationic amphiphilic drugs can induce the accumulation of phospholipids in multi-lamellar bodies which is associated with clinical toxicities (e.g. hepatotoxicity, cardiac arrhythmias, kidney or lung injury, and myopathies). For a predictive risk assessment of drug candidates animal testing is still...

Allergic contact dermatitis is an environmental health issue induced by chemicals which have been identified as skin sensitizers. Recently a set of alternative methods has been punblished by OECD replacing the animal local lymph node assay. The cell based assays represent early key events of the...

Recombinant cell lines expressing human ion channels for cardiac safety testing and other applications have been licensed from B'SYS Switzerland for the preparation of patch ready cells. These cells are ready to use after thawing for automated and manual patch clamp set-ups and do no need to be...

Kidney epithelial cells from the proximal part of the tubulus are and essential tool to specifically asses nephrotoxicity in vitro. ciPTEC cells are conditionally immortalized proximal tubular epithelial cells developed by the Radbound University Nijmegen (NL). The activity of two kidney specific...