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Recombinant cell lines expressing human ion channels for cardiac safety testing and other applications have been licensed from B'SYS Switzerland for the preparation of patch ready cells. These cells are ready to use after thawing for automated and manual patch clamp set-ups and do no need to be...

Allergic contact dermatitis is an environmental health issue induced by chemicals which have been identified as skin sensitizers. Recently a set of alternative methods has been published by the OECD replacing the animal local lymph node assay. The cell based assays represent early key events of the...

Kidney epithelial cells from the proximal part of the tubulus are an essential tool to specifically assess nephrotoxicity in vitro. ciPTEC cells are conditionally immortalized proximal tubular epithelial cells developed by the Radbound University Nijmegen (NL). The activity of two kidney specific...

Medical devices and material which comes in contact with a patient must be tested for biocompatibility before a product can be released for the market. As part of this, the cytotoxicity of extracts prepared from the materials is addressed. Sensitive indicator cells like L-929 mouse fibroblasts are...