instaCELL® G-CSF Potency Assay Kit

The instaCELL G-CSF potency assay kit is an in vitro test to determine the potency of Granulocyte Colony Stimulation Factor (G-CSF) formulations for quality control. Recombinant forms of G-CSF are used in medicine to treat conditions associated with neutropenia (a low neutrophil count), such as chemotherapy-induced neutropenia, myelodysplastic syndromes, and bone marrow transplantation. The assay utilizes the cytokine dependence of NFS-60 cells, a murine myeloid progenitor cell line, for their proliferation, which make them a valid model to determine the potency of cytokines like G-CSF in a proliferation bioassay. The assay kit uses a Resazurin viability assay to analyze the potency of the G-CSF product and compares it to a kit included reference.

The instaCELL G-CSF assay kit includes prequalified NFS-60 instaCELLs as well as media, reagents, reference standard, and 96-well plate. InstaCELLs are frozen cell aliquots which can be used directly in the assay without prior cultivation, basically like a reagent.

G-CSF Potency Assay Kit

instaCELL® G-CSF Potency Assay Kit (SF330-01)

NFS-60 assay ready cells
Assay Buffer G, Recovery Buffer G
G-CSF Reference
Resazurin viability dye
96-well assay plate

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