products

AssayWorks, Germany has developed a set of recombinant cell lines expressing pharmaceutically relevant receptors and ion channels. The targets are commonly used for small molecule compound screening, lead identification, and selectivity testing. acCELLerate provides these cell lines in assay ready...

Chemicals or other environmental noxes which damage the DNA or interfere with cell division, may impact the genomic integrity of cells. This can result in cell death and cancer. To screen chemicals for their genotoxic and mutagenic potential multiple types of assays have been developed. A cell‐based...

Drug induced accumulation of phospholipids (phospholipidosis) is associated with clinical toxicities. Cell‐based assays can help to evaluate the phospholipidosis risk of a drug at an early stage of preclinical development and may reduce animal testing. The instaCELL Phospholipidosis Assay Kits...

The monocyte activation test (MAT) is used to detect or quantify substances that activate human monocytes to release endogenous mediators such as pro-inflammatory cytokines like tumor necrosis factor alpha (TNFα) which play an important role in fever pathogenesis. The MAT assay detects the presence...