products

AssayWorks, Germany has developed a set of recombinant cell lines expressing pharmaceutically relevant receptors and ion channels. The targets are commonly used for small molecule compound screening, lead identification, and selectivity testing. acCELLerate provides these cell lines in assay ready...

Expanded Primary Cells have been developed to give researchers the opportunity to work with cells which closely resemble the in vivo situation. The cells are brought back into proliferation without altering their most relevant tissue-specific characteristics such as transporters or enzyme...

Patch Ready Cells are pre‐qualified aliquots of cryopreserved cells which can be used in patch clamp assays without prior cultivation. The set of cell lines expresses pharmaceutically relevant ion channels including the six cardiac channels of the CiPA panel. The ion channel cell lines have been...

instaCELL cytotoxicity assay kits have been designed to improve the reliability and reproducibility of routine toxicity testing. The assay kit includes aliquots of cryopreserved assay ready cells which have been qualified for the testing. The cells can be used like a reagent instantly after thawing...

Chemicals or other environmental noxes which damage the DNA or interfere with cell division, may impact the genomic integrity of cells. This can result in cell death and cancer. To screen chemicals for their genotoxic and mutagenic potential multiple types of assays have been developed. A cell‐based...

Drug induced accumulation of phospholipids (phospholipidosis) is associated with clinical toxicities. Cell‐based assays can help to evaluate the phospholipidosis risk of a drug at an early stage of preclinical development and may reduce animal testing. The instaCELL Phospholipidosis Assay Kits...

The monocyte activation test (MAT) is used to detect or quantify substances that activate human monocytes to release endogenous mediators such as pro-inflammatory cytokines like tumor necrosis factor alpha (TNFα) which play an important role in fever pathogenesis. The MAT assay detects the presence...

A new generation of microplate absorbance readers captivates with their small footprint and innovative set-up. Within seconds, a compact system without moving parts composed out of 4 LEDs and 96 photodiodes allows the simultaneous reading of the individual signals from a 96-well plate. The built-in...