products

A possible genotoxic effect should be discovered as early as possible in the development of a new drug to avoid unnecessary costs. The instaCELL® micronucleus assay kit, based on OECD guideline 487, is a simple and quick method to determine the genotoxic potential of a candidate substance. The...

Medical devices and material which comes in contact with a patient must be tested for biocompatibility before a product can be released for the market. As part of this, the cytotoxicity of extracts prepared from the materials is addressed. Sensitive indicator cells like L-929 mouse fibroblasts are...

Drug induced accumulation of phospholipid (phospholipidosis) is associated with clinical toxicities and animal testing is still required for a predictive risk assessment. However, in silico models and cell-based assays can help to evaluate the phospholipidosis potential of a drug at an early stage...

A new generation of microplate absorbance readers captivates with their small footprint and innovative set-up. Within
seconds, a compact system without moving parts composed out of 4 LEDs and 96 photodiodes allows the simultaneous
reading of the individual signals from a 96-well p late. The built-in...

ARC ‐ Assay Ready Cells have been developed to release you from preparatory cell culture work and to provide you with a better flexibility to schedule your experiments. ARCs are cryopreserved at a highly functional state and can be used instantly after thawing like other reagents you are using in...

acCELLerate distributes a growing list of recombinant target expressing cell lines provided by assay works. The cell lines cover a broad range of pharmaceutically relevant transmembrane proteins (GPCR's ion channels transporter) generally used for small molecule compound screening lead...

Recombinant cell lines that functionally express human ion channels are a valuable tool to screen for drugs targeting pain, stroke, or metabolic diseases but also to test candidates for negative side effects that induce proarrhythmia (CIPA panel). A set of six sodium and potassium channel cell lines...

Kidney epithelial cells from the proximal part of the tubulus are an essential tool to specifically assess nephrotoxicity in vitro. ciPTEC cells are conditionally immortalized proximal tubular epithelial cells developed by the Radbound University Nijmegen (NL). The activity of two kidney specific...