products

ARC ‐ assay ready cells have been developed to release you from preparatory cell culture work and to provide you with a better flexibility to schedule your experiments. ARCs are cryopreserved at a highly functional state and can be used instantly after thawing like other reagents you are using in...

acCELLerate distributes a growing list of recombinant target expressing cell lines provided by assay works. The cell lines cover a board range of pharmaceutically relevant transmembrane prtoeins (GPCR's ion channels transporter) generically used for small molecule compound screening lead...

ChromoTek’s Chromobodies are fluorescent nanoprobes for real-time and live-cell imaging of intracellular endogenous proteins. A Chromobody is a small intracellular functional antibody fused to a fluorescent protein. Unlike conventional antibodies Chromobodies non-invasively...

Medical devices and material which comes in contact with a patient must be tested for biocompatibility before a product can released for the market. As part of this, the cytotoxicity of extracts prepared from the materials is addressed. Sensitive indicator cells like L-929 mouse fibroblasts are...

Cationic amphiphilic drugs can induce the accumulation of phospholipids in multi-lamellar bodies which is associated with clinical toxicities (e.g. hepatotoxicity, cardiac arrhythmias, kidney or lung injury, and myopathies). For a predictive risk assessment of drug candidates animal testing is still...

Recombinant cell lines expressing human ion channels for cardiac safety testing and other applications have been licensed from B'SYS Switzerland for the preparation of patch ready cells. These cells are ready to use after thawing for automated and manual patch clamp set-ups and do no need to be...

RRC ‐ reporter ready cells are transfected with a luciferase reporter gene which is expressed upon activation of stress pathways e.g. NFκB inflammation response or Nrf‐2 antioxidant response. The cells have been frozen right after transfection in a way that they are ready‐to-use for the reporter...

Kidney epithelial cells from the proximal part of the tubulus are and essential tool to specifically asses nephrotoxicity in vitro. ciPTEC cells are conditionally immortalized proximal tubular epithelial cells developed by the Radbound University Nijmegen (NL). The activity of two kidney specific...